SCHEMBL1057997

SCHEMBL1057997

CCCN(CCCS(=O)(=O)O)c1ccc(N=Nc2ccc(Br)cn2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 13/20 0.49
▸ RIOK2 Q9BVS4 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652162 1.00 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL3424094 1.00 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL29652161 1.00 KCNH2 (0.49) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL3173642 0.99 KCNH2 (0.48) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL3173652 0.99 KCNH2 (0.48) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL6212285 0.99 KCNH2 (0.48) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL4207580 0.99 KCNH2 (0.48) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL3173648 0.91 KCNH2 (0.41) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL4207578 0.91 KCNH2 (0.41) KCNH2RIOK2KDM4EALDH1A1POLB
SCHEMBL29743296 0.91 KCNH2 (0.41) KCNH2RIOK2KDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4244385-B1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MULTIPLEXDX S R O (SK) 2025-01-01 — — EP claimed
CN-118435055-A Compositions and methods for detecting enzymatic pyrophosphate products using pyridine azo aniline dyes 新英格兰生物实验室公司 2024-08-02 — — CN claimed
US-20240026435-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2024-01-25 — — US claimed
CN-117417986-A Method for rapidly detecting target nucleic acid sequence based on 5-Br-PAPS 浙江大学杭州国际科创中心 2024-01-19 — — CN claimed
CN-116802315-A Loop-mediated isothermal nucleic acid amplification (LAMP) using LNA modified primers and metal-based colorimetric detection of amplified products 马尔提普莱克斯公司 2023-09-22 — — CN claimed
EP-4244385-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2023-09-20 — — EP claimed
WO-2023076772-A1 COMPOSITIONS AND METHODS FOR DETECTING PYROPHOSPHATE PRODUCTS OF ENZYME REACTIONS USING PYRIDYLAZOANILINE DYES NEW ENGLAND BIOLABS, INC. (US) 2023-05-04 — — WO claimed
EP-4174491-A1 COMPOSITIONS AND METHODS FOR DETECTING PYROPHOSPHATE PRODUCTS OF ENZYME REACTIONS USING PYRIDYLAZOANILINE DYES NEW ENGLAND BIOLABS, INC. (US) 2023-05-03 — — EP claimed
US-11512342-B1 Compositions and methods for detecting pyrophosphate products of enzyme reactions using pyridylazoaniline dyes NEW ENGLAND BIOLABS, INC. (US) 2022-11-29 — — US claimed
WO-2022101259-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2022-05-19 — — WO claimed
US-20110046204-A1 Human Zip1, Zinc and Citrate for Prostate Cancer Screening UNIVERSITY OF MARYLAND, BALITMORE 2011-02-24 — — US claimed
US-20110020943-A1 DRY TESTING TOOL, METHOD FOR MEASURING METAL, AND METHOD FOR PRODUCING DRY TESTING TOOL ARKRAY, INC. (JP) 2011-01-27 — — US claimed
EP-2261656-A1 DRY TEST INSTRUMENT, METHOD OF MEASURING METAL AND METHOD OF PRODUCING DRY TEST INSTRUMENT ARKRAY, Inc. (JP) 2010-12-15 — — EP claimed
US-20100061891-A1 Flow analysis system capable of quantitatively or semi-quantitatively determining element in sample CANON SEMICONDUCTOR EQUIPMENT INC. (JP) 2010-03-11 — — US claimed
EP-1977248-A4 HUMAN ZIP1, ZINC AND CITRATE FOR PROSTATE CANCER SCREENING UNIV MARYLAND (US) 2009-08-05 — — EP claimed
US-20090017545-A1 Method of Determining Metal by Colorimetry and Determination Reagent SHINO-TEST CORPORATION (JP) 2009-01-15 — — US claimed
EP-1992943-A1 METHOD OF DETERMINING METAL BY COLORIMETRY AND DETERMINATION REAGENT SHINO-TEST CORPORATION (JP) 2008-11-19 — — EP claimed
EP-1977248-A2 HUMAN ZIP1, ZINC AND CITRATE FOR PROSTATE CANCER SCREENING THE UNIVERSITY OF MARYLAND AT BALTIMORE (US) 2008-10-08 — — EP claimed
US-20070292900-A1 Zinc-based screening test and kit for early diagnosis of prostate cancer ANDRO DIAGNOSTICS, INC. 2007-12-20 — — US claimed
WO-2007087263-A2 HUMAN ZIP1, ZINC AND CITRATE FOR PROSTATE CANCER SCREENING THE UNIVERSITY OF MARYLAND, BALTIMORE (US) 2007-08-02 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090017545-A1 Method of Determining Metal by Colorimetry and Determination Reagent FECH, SLC30A5, SLC30A6 KCNH2 2344/4885RIOK2 4600/4885KDM4E 2407/4885
US-20110046204-A1 Human Zip1, Zinc and Citrate for Prostate Cancer Screening SLC39A11, SLC39A3, SLC30A5 KCNH2 3722/4885RIOK2 4319/4885KDM4E 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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