Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173642 | 1.00 | KCNH2 (0.48) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL6212285 | 1.00 | KCNH2 (0.48) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL29652162 | 0.99 | KCNH2 (0.49) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL1057997 | 0.99 | KCNH2 (0.49) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL29652161 | 0.99 | KCNH2 (0.49) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL3424094 | 0.99 | KCNH2 (0.49) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL3173652 | 0.98 | KCNH2 (0.48) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL3173648 | 0.90 | KCNH2 (0.41) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL29743296 | 0.90 | KCNH2 (0.41) | KCNH2RIOK2KDM4EALDH1A1POLB | |
| SCHEMBL4207578 | 0.90 | KCNH2 (0.41) | KCNH2RIOK2KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969613-B1 | Method for determination of hydrogen sulfide or sulfide ion and method for determination of specific substance utilizing said method | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2005-11-29 | — | — | US | claimed |
| US-20090017545-A1 | Method of Determining Metal by Colorimetry and Determination Reagent | SHINO-TEST CORPORATION (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-1992943-A1 | METHOD OF DETERMINING METAL BY COLORIMETRY AND DETERMINATION REAGENT | SHINO-TEST CORPORATION (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1555530-B1 | Method for quantitatively determining homocysteine and a reagent for quantitative determination of homocysteine | DAIICHI PURE CHEMICALS CO LTD (JP) | 2006-08-23 | — | — | EP | disclosed |
| US-6969613-B1 | Method for determination of hydrogen sulfide or sulfide ion and method for determination of specific substance utilizing said method | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| EP-1555530-A1 | Method for quantitatively determining homocysteine and a reagent for quantitative determination of homocysteine | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20050153385-A1 | Method for quantitatively determining homocysteine and a reagent for quantitative determination of homocysteine | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1143244-B1 | METHOD FOR DETERMINATION OF HYDROGEN SULFIDE OR SULFIDE ION AND METHOD FOR DETERMINATION OF SPECIFIC SUBSTANCE UTILIZING SAID METHOD | DAIICHI PURE CHEMICALS CO LTD (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1143244-A1 | METHOD FOR DETERMINATION OF HYDROGEN SULFIDE OR SULFIDE ION AND METHOD FOR DETERMINATION OF SPECIFIC SUBSTANCE UTILIZING SAID METHOD | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-0642021-B1 | Process for measuring complement activity and reagent used therefor | WAKO PURE CHEM IND LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-6015679-A | REACTING LIPOSOMES HAVING ENCAPSULATED MARKER AND A HAPTEN IMMOBILIZED ON ITS SURFACE WITH AN UNBOUND ANTIBODY AND A SAMPLE CAUSING RUPTURING OF LIPOSOMES, MEASURING AMOUNT OF RELEASED MARKER AS INDICATOR OF ACTIVITY | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| US-5854082-A | Process for measuring complement activity and reagent used therefor | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0475786-B1 | Method for determination of antistreptolysin O | WAKO PURE CHEM IND LTD (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0382400-B1 | Immunoassay process and liquid reagents used therefor | WAKO PURE CHEM IND LTD (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0642021-A2 | Process for measuring complement activity and reagent used therefor | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5221613-A | Lysis of microcapsules | WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0475786-A2 | Method for determination of antistreptolysin O | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1992-03-18 | — | — | EP | disclosed |
| EP-0382400-A2 | Immunoassay process and liquid reagents used therefor | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017545-A1 | Method of Determining Metal by Colorimetry and Determination Reagent | FECH, SLC30A5, SLC30A6 | KCNH2 2344/4885RIOK2 4600/4885KDM4E 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.