Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.43 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387432 | 0.82 | PDE7A (0.71) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL29485957 | 0.79 | LMNA (0.59) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL1119379 | 0.79 | LMNA (0.59) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL28115044 | 0.77 | PDE7A (0.56) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL5863266 | 0.76 | PDE7A (0.82) | PDE7AMAPK1TSHRKDM4ELMNA | |
| SCHEMBL3654191 | 0.76 | PDE7A (0.63) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL29780387 | 0.76 | PDE7A (0.82) | PDE7AMAPK1TSHRKDM4ELMNA | |
| SCHEMBL28486904 | 0.75 | PDE7A (0.54) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL15077840 | 0.75 | PDE7A (0.54) | PDE7AMAPK1TSHRVCAM1S1PR4 | |
| SCHEMBL19175613 | 0.75 | PDK1 (0.61) | PDE7AMAPK1TSHRVCAM1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859713-A | Production of flame-retardant polyols | BLOUNT DAVID H (US) | 1989-08-22 | — | — | US | disclosed |