Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580436 | 0.89 | USP2 (0.49) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10578217 | 0.80 | USP2 (0.50) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL16399040 | 0.77 | ALDH1A1 (0.57) | USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL9211612 | 0.77 | ALDH1A1 (0.57) | USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL9214287 | 0.77 | ALDH1A1 (0.57) | USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL62391 | 0.77 | ALDH1A1 (0.57) | USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL16402730 | 0.77 | ALDH1A1 (0.57) | USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL10578243 | 0.70 | USP2 (0.53) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL16398934 | 0.70 | USP2 (0.53) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL6772647 | 0.70 | FFAR4 (0.50) | FFAR4FFAR1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855322-A | ANTIANDROGENS;SKIN DISORDERS | CBD CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| US-4689345-A | ANTIANDROGENS | CBD CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |
| US-4689349-A | Anti-tumor halo bicyclo alkanones | CBD CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |