SCHEMBL62391

SCHEMBL62391

CCCCCCC1C=CCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
USP2 O75604 1/20 0.57
ALOX15 P16050 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
EPHX1 P07099 1/20 0.41
PSMB11 A5LHX3 3/20 0.38
PSMA7 O14818 3/20 0.38
PSMB1 P20618 3/20 0.38
PSMA1 P25786 3/20 0.38
PSMA2 P25787 3/20 0.38
PSMA3 P25788 3/20 0.38
PSMA4 P25789 3/20 0.38
PSMB8 P28062 3/20 0.38
PSMB9 P28065 3/20 0.38
PSMA5 P28066 3/20 0.38
PSMB4 P28070 3/20 0.38
PSMB6 P28072 3/20 0.38
PSMB5 P28074 3/20 0.38
PSMB10 P40306 3/20 0.38
PSMB3 P49720 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202780 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL9214287 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL16399040 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL11788866 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL9209673 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL11785211 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL16402730 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL9211612 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL9213351 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1
SCHEMBL9207936 1.00 ALDH1A1 (0.57) ALDH1A1USP2ALOX15TDP1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218633-A1 METHODS OF TREATING ORAL MUCOSITIS GALERA LABS, LLC 2023-07-13 US disclosed
US-11612608-B2 Methods of treating oral mucositis GALERA LABS, LLC (US) 2023-03-28 US disclosed
US-20200215077-A1 METHODS OF TREATING ORAL MUCOSITIS BIOSSIL INC. (CA) 2020-07-09 US disclosed
US-10610533-B2 Methods of treating oral mucositis GALERA LABS, LLC (US) 2020-04-07 US disclosed
EP-3527079-A1 METHODS OF TREATING ORAL MUCOSITIS Galera Labs, LLC (US) 2019-08-21 EP disclosed
EP-2056675-B1 METHODS OF TREATING ORAL MUCOSITIS GALERA LABS LLC (US) 2019-01-09 EP disclosed
US-20180333421-A1 METHODS OF TREATING ORAL MUCOSITIS BIOSSIL INC. (CA) 2018-11-22 US disclosed
EP-3287464-A1 ONE POT SYNTHESIS OF TETRAZOLE DERIVATIVES OF SIROLIMUS Abbott Laboratories (US) 2018-02-28 EP disclosed
US-9855279-B2 Methods of treating oral mucositis GALERA LABS, LLC (US) 2018-01-02 US disclosed
EP-2859916-B1 Combination of an antimitotic agent and a selective superoxide dismutase mimetic in antitumor therapy GALERA LABS LLC (US) 2017-11-29 EP disclosed
EP-0756495-A1 DIAGNOSTIC IMAGE ANALYSIS WITH METAL COMPLEXES MONSANTO COMPANY (US) 1997-02-05 EP disclosed
WO-1996040658-A1 PROCESS FOR PREPARING SUBSTITUTED POLYAZAMACROCYCLES MONSANTO COMPANY (US) 1996-12-19 WO disclosed
WO-1996039396-A1 MANGANESE OR IRON COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1996-12-12 WO disclosed
WO-1995028968-A1 DIAGNOSTIC IMAGE ANALYSIS WITH METAL COMPLEXES MONSANTO COMPANY (US) 1995-11-02 WO disclosed
EP-0679155-A1 MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE. MONSANTO CO (US) 1995-11-02 EP disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
WO-1994015925-A1 MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1994-07-21 WO disclosed
EP-0524161-A1 Manganese complexes of nitrogen containing macrocyclic ligands effective as catalysts for dismutating superoxide MONSANTO COMPANY (US) 1993-01-20 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180333421-A1 METHODS OF TREATING ORAL MUCOSITIS LPO, SOD3, MPO ALDH1A1 664/4885USP2 1557/4885ALOX15 540/4885
US-20200215077-A1 METHODS OF TREATING ORAL MUCOSITIS LPO, SOD3, MPO ALDH1A1 664/4885USP2 1557/4885ALOX15 540/4885
US-20230218633-A1 METHODS OF TREATING ORAL MUCOSITIS LPO, SOD3, MPO ALDH1A1 664/4885USP2 1557/4885ALOX15 540/4885
US-10610533-B2 Methods of treating oral mucositis LPO, SOD3, MPO ALDH1A1 664/4885USP2 1557/4885ALOX15 540/4885
US-11612608-B2 Methods of treating oral mucositis LPO, SOD3, MPO ALDH1A1 664/4885USP2 1557/4885ALOX15 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.