Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476339 | 0.66 | PIK3CD (0.47) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10581989 | 0.65 | — | — | |
| SCHEMBL18659057 | 0.64 | — | — | |
| SCHEMBL11408696 | 0.64 | — | — | |
| SCHEMBL21950819 | 0.62 | LMNA (0.38) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3674153 | 0.62 | LMNA (0.38) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10640680 | 0.62 | NPC1 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8172810 | 0.62 | TSHR (0.32) | — | |
| SCHEMBL9739418 | 0.61 | LMNA (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4126996 | 0.61 | PIK3CD (0.59) | PIK3CDCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301877-A1 | A method of deprotection of 3-amino azetidinones | ELI LILLY AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |