Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.79 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | P4HB | P07237 | 5/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582957 | 1.00 | ABCG2 (0.79) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL15807424 | 0.90 | ABCG2 (0.63) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL14306013 | 0.87 | ABCG2 (0.79) | ABCG2TNFRSF1ALMNAMAPTABCB1 | |
| SCHEMBL15807742 | 0.86 | P4HB (0.83) | ABCG2TNFRSF1AMEN1KMT2AABCB1 | |
| SCHEMBL25221520 | 0.85 | P4HB (0.73) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL30384349 | 0.85 | P4HB (0.73) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL30382589 | 0.85 | P4HB (0.73) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL25285091 | 0.85 | P4HB (0.73) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL2458577 | 0.84 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL2458579 | 0.84 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307762-A1 | Acrylic-acid amides and their use as fungicides | F. HOFFMANN-LA ROCHE AG (CH) | 1989-03-22 | — | — | EP | disclosed |