Aminothiazole

Aminothiazole

SCHEMBL10585434

CC(C)=O.Nc1nccs1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
TSHR P16473 1/20 0.71
NOS1 P29475 1/20 0.71
HSD17B10 Q99714 1/20 0.71
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 2/20 0.38
HIF1A Q16665 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
AGER Q15109 1/20 0.38
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminothiazole SCHEMBL1003511 0.93 ALDH1A1 (0.68) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL4466019 0.93 ALDH1A1 (0.68) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL5907075 0.91 ALDH1A1 (0.65) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL28215372 0.91 ALDH1A1 (0.65) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL28380726 0.91 ALDH1A1 (0.65) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL28006118 0.89 ALDH1A1 (0.62) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL5907076 0.89 ALDH1A1 (0.62) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL1241596 0.88 ALDH1A1 (0.75) ALDH1A1TSHRNOS1HSD17B10NPC1
Aminothiazole SCHEMBL27943753 0.87
Aminothiazole SCHEMBL27377990 0.87 ALDH1A1 (0.60) ALDH1A1TSHRNOS1HSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326050-A1 Abrasion resistant resilient backing BASF Aktiengesellschaft (DE) 1989-08-02 EP disclosed