Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401272 | 0.93 | DUSP3 (0.35) | DUSP3PTPN5PTPN11CTDSP1AKR1B1 | |
| SCHEMBL4674767 | 0.84 | DUSP3 (0.35) | DUSP3PTPN5PTPN11CTDSP1AKR1B1 | |
| SCHEMBL15948192 | 0.78 | AKR1B1 (0.42) | AKR1B1KDM4ELMNAFOLH1 | |
| SCHEMBL15948206 | 0.76 | AKR1B1 (0.41) | AKR1B1KDM4ELMNAFOLH1 | |
| SCHEMBL503968 | 0.76 | AKR1B1 (0.41) | AKR1B1KDM4EFOLH1 | |
| SCHEMBL336420 | 0.75 | CES2 (0.42) | KDM4EASPHKDM8LMNA | |
| SCHEMBL16673166 | 0.75 | KDM4E (0.42) | KDM4EASPHKDM8 | |
| SCHEMBL141037 | 0.75 | CYP1A2 (0.40) | KDM4EASPHKDM8LMNA | |
| SCHEMBL542568 | 0.75 | MEN1 (0.35) | POLB | |
| SCHEMBL15948146 | 0.74 | AKR1B1 (0.39) | AKR1B1KDM4EFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319906-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |