SCHEMBL503968

SCHEMBL503968

O=C(O)Cc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 3/20 0.41
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
FOLH1 Q04609 1/20 0.35
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33
CA2 P00918 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15948146 0.97 AKR1B1 (0.39) AKR1B1TAS1R3TAS1R1TAS1R2FOLH1
SCHEMBL15948192 0.97 AKR1B1 (0.42) AKR1B1TAS1R3TAS1R1TAS1R2FOLH1
SCHEMBL15948206 0.94 AKR1B1 (0.41) AKR1B1TAS1R3TAS1R1TAS1R2FOLH1
SCHEMBL4103547 0.85 IMPDH2 (0.39) AKR1B1TAS1R3TAS1R1TAS1R2KDM4E
SCHEMBL11268242 0.85 CYP1A2 (0.37) AKR1B1HSD17B10CA2CYP1A2
SCHEMBL27762098 0.85 CSNK2A2 (0.41) AKR1B1TAS1R3TAS1R1TAS1R2MEN1
SCHEMBL4674767 0.83 DUSP3 (0.35) AKR1B1FOLH1MEN1KMT2A
SCHEMBL29142080 0.81 SMN1; SMN2 (0.53) AKR1B1MEN1KMT2ATSHRAGBL2
SCHEMBL12445751 0.79 CYP1A2 (0.37) AKR1B1KDM4EALDH1A1GAAGLA
SCHEMBL22344509 0.79 AKR1B1 (0.35) AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-120199973-A Polyvinylidene fluoride composite diaphragm for zinc battery and preparation method and application thereof 中国科学院赣江创新研究院 2025-06-24 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118290254-A Rare earth complex for zinc battery electrolyte and preparation method and application thereof 中国科学院赣江创新研究院 2024-07-05 CN claimed
CN-115939514-A Hydrolysis-resistant functional additive, preparation method thereof and application thereof in solid electrolyte 华南理工大学 2023-04-07 CN claimed
CN-111135810-B Preparation method of special chromatographic separation medium for cannabidiol separation 苏州汇通色谱分离纯化有限公司 2022-08-23 CN claimed
WO-2022163846-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE 第一三共株式会社 2022-08-04 WO claimed
CN-111135810-A Preparation method of special chromatographic separation medium for cannabidiol separation 苏州汇通色谱分离纯化有限公司 2020-05-12 CN claimed
EP-3114715-B1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS SIEMENS AG (DE) 2019-10-30 EP claimed
EP-1051506-B2 PROCEDURES FOR THE EXTRACTION AND ISOLATION OF BACTERIAL CAPSULAR POLYSACCHARIDES FOR USE AS VACCINES OR LINKED TO PROTEINS AS CONJUGATES VACCINES PFIZER IRELAND PHARMACEUTICALS (IE) 2019-08-21 EP claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-0705279-B1 TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES SELECTIDE CORP (US) 2003-02-19 EP claimed
EP-1022952-A4 HIGH PURITY ALKOXYTRIMETHYLSILANE FLUIDS CLARIANT LSM ITALIA SPA (US) 2002-08-14 EP claimed
EP-1022952-A1 HIGH PURITY ALKOXYTRIMETHYLSILANE FLUIDS ARCHIMICA (FLORIDA), Inc. (US) 2000-08-02 EP claimed
WO-1999017615-A1 HIGH PURITY ALKOXYTRIMETHYLSILANE FLUIDS ARCHIMICA (FLORIDA) INC. (US) 1999-04-15 WO claimed
US-5847179-A High purity alkoxytrimethylsilane fluids PCR, INC. (US) 1998-12-08 US claimed
US-5750568-A DITERPENE PHORBOIDS PROCYON PHARMACEUTICALS, INC. (US) 1998-05-12 US claimed
US-5214218-A Montmorillonite clays TEXACO CHEMICAL COMPANY (US) 1993-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 AKR1B1 1963/4885TAS1R3 1889/4885TAS1R1 2623/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 AKR1B1 2784/4885TAS1R3 1031/4885TAS1R1 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.