Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583917 | 0.81 | CYP1A2 (0.50) | FAPABCB11POLA1POLGSLC22A6 | |
| SCHEMBL10364108 | 0.77 | ACHE (0.40) | FGFR1FGFR4HDAC6PDE3ACYP3A4 | |
| SCHEMBL9592643 | 0.76 | FGFR1 (0.40) | FGFR1FGFR4FDPSHDAC6P2RX7 | |
| SCHEMBL8846475 | 0.74 | ADORA2A (0.56) | CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9583095 | 0.74 | CCNE1 (0.48) | HDAC6FAPABCB11POLA1POLG | |
| SCHEMBL9575550 | 0.72 | ACHE (0.42) | FGFR1FGFR4HDAC6P2RX7PDE3A | |
| SCHEMBL9583892 | 0.72 | ADORA2A (0.53) | FAPPDE3ACYP3A4ALDH1A1 | |
| SCHEMBL9583614 | 0.71 | MEN1 (0.68) | PDE3ACYP3A4MEN1ALDH1A1LMNA | |
| SCHEMBL9584969 | 0.71 | PDE3A (0.44) | HDAC6FAPABCB11POLA1POLG | |
| SCHEMBL10585084 | 0.70 | PDE3A (0.42) | FGFR1PDE3ACYP3A4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306845-A2 | Medicinal preparation containing certain derivatives of 6-mercaptopurine, use of these derivatives of 6-mercaptopurine, process for the preparation of the medicinal preparation and some derivatives of 6-mercaptopurine and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-15 | — | — | EP | disclosed |