Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405793 | 0.90 | ACHE (0.44) | ACHEPDE3AMEN1KMT2ATSHR | |
| SCHEMBL9575530 | 0.89 | ACHE (0.43) | ACHEMEN1KMT2ATSHRHDAC1 | |
| SCHEMBL10364108 | 0.86 | ACHE (0.40) | ACHEPDE3AMEN1KMT2ATSHR | |
| SCHEMBL9575560 | 0.86 | ACHE (0.40) | ACHEPDE3AMEN1KMT2ATSHR | |
| SCHEMBL9575342 | 0.86 | ACHE (0.43) | ACHEMEN1KMT2ATSHRHDAC1 | |
| SCHEMBL9575539 | 0.85 | MEN1 (0.48) | ACHEMEN1KMT2ATSHRBLM | |
| SCHEMBL9021299 | 0.83 | ACHE (0.42) | ACHE | |
| SCHEMBL9575559 | 0.81 | ALDH1A1 (0.41) | PDE3AMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9575536 | 0.80 | ACHE (0.43) | ACHEMEN1KMT2ATSHRHDAC1 | |
| SCHEMBL8711549 | 0.79 | ACHE (0.40) | ACHEMEN1KMT2ATSHRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |