Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.55 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360302 | 0.78 | GABBR2 (0.54) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL5140906 | 0.76 | GABBR2 (0.56) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL6351937 | 0.75 | GABBR2 (0.50) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL9336332 | 0.73 | GABBR2 (0.48) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL9417053 | 0.73 | GABBR2 (0.48) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL9336341 | 0.72 | LMNA (0.50) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL2353617 | 0.71 | GABBR2 (0.83) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL7645645 | 0.71 | LMNA (0.54) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| Sgs-742 SCHEMBL195133 | 0.71 | GABBR2 (1.00) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL6351264 | 0.70 | GABBR2 (0.87) | GABBR2GABBR1GABRR1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319479-A2 | Substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | claimed |
| EP-0319482-A2 | Novel substituted propane phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | claimed |