SCHEMBL10586455

SCHEMBL10586455

CNC(=O)Nc1ccc([C]=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
KMT2A Q03164 5/20 0.53
POLB P06746 3/20 0.49
SAE1 Q9UBE0 1/20 0.47
UBA2 Q9UBT2 1/20 0.47
RAB9A P51151 5/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MEN1 O00255 3/20 0.47
HPGD P15428 2/20 0.47
CYP2C19 P33261 1/20 0.47
RECQL P46063 1/20 0.45
MAPT P10636 5/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
NLRP3 Q96P20 1/20 0.44
PKM P14618 1/20 0.43
MAPK1 P28482 1/20 0.43
IL18 Q14116 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10155599 0.85 ALDH1A1 (0.78) ALDH1A1KMT2APOLBSAE1UBA2
SCHEMBL1542345 0.82 ALDH1A1 (0.58) ALDH1A1KMT2APOLBSAE1UBA2
SCHEMBL6125249 0.82 SAE1 (0.69) ALDH1A1KMT2APOLBSAE1UBA2
SCHEMBL10586715 0.79 MTNR1B (0.48) ALDH1A1KMT2ASAE1UBA2RAB9A
SCHEMBL599684 0.79 KMT2A (0.73) ALDH1A1KMT2APOLBRAB9ASMN1; SMN2
SCHEMBL20852214 0.79 ALDH1A1 (0.69) ALDH1A1KMT2APOLBSAE1UBA2
SCHEMBL10680071 0.78 MEN1 (0.55) ALDH1A1KMT2APOLBSAE1UBA2
SCHEMBL172125 0.77 ALDH1A1 (0.67) ALDH1A1KMT2APOLBRAB9ASMN1; SMN2
SCHEMBL18814508 0.77 KMT2A (0.67) ALDH1A1KMT2APOLBRAB9ASMN1; SMN2
SCHEMBL2718417 0.77 ALDH1A1 (0.67) ALDH1A1KMT2APOLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0319999-A2 Silver halide photographic materials Fuji Photo Film Co., Ltd. (JP) 1989-06-14 EP disclosed
US-4764455-A Color image-forming process FUJI PHOTO FILM CO., LTD. (JP) 1988-08-16 US disclosed