SCHEMBL105869

SCHEMBL105869

C=CC(=O)NC(CO)(CO)CO

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.44
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
TGM2 P21980 3/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637582 0.89 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL16900645 0.87 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL275376 0.87 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL7037814 0.87 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL17506759 0.83 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL7740515 0.83 TSHR (0.38) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL15694287 0.82 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL8841271 0.82 ALDH1A1 (0.31) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL23646842 0.81 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL14366076 0.80 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4116 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060115-A Main agent of water-blocking polymer, gel water-blocking agent, preparation method and application thereof 中国石油集团渤海钻探工程有限公司 2026-05-19 CN claimed
US-20260114246-A1 FABRICATION METHODS OF SEMICONDUCTOR STRUCTURES SEMICONDUCTOR MFG INT SHANGHAI CORP (CN) 2026-04-23 US claimed
US-20260114247-A1 FABRICATION METHODS OF SEMICONDUCTOR STRUCTURES SEMICONDUCTOR MFG INT SHANGHAI CORP (CN) 2026-04-23 US claimed
EP-4722195-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLES National University Corporation Hokkaido University (JP) 2026-04-08 EP claimed
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP claimed
US-12595396-B2 Acid resistant filter media ENTEGRIS, INC. (US) 2026-04-07 US claimed
CN-121574286-A Acid-triggered step-by-step bonding high molecular tissue adhesive and preparation method and application thereof 西安交通大学 2026-02-27 CN claimed
EP-3416626-B1 MICROSPHERES FOR USE IN THERAPEUTIC EMBOLIZATION BIOSPHERE MEDICAL INC (US) 2026-02-25 EP claimed
US-20260042870-A1 BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2026-02-12 US claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
WO-1988009981-A2 POLYMERS, AND THEIR USE AS GELS FOR ELECTROPHORESIS KOZULIC BRANKO (CH) 1988-12-15 WO claimed
US-4753983-A Polymeric matrix for affinity chromatography and immobilization of ligands BIOPROBE INTERNATIONAL, INC. (US) 1988-06-28 US claimed
EP-0268973-A2 Process for manufacturing a virus-free, stable and intravenously tolerant immunoglobulin-G preparation Biotest Pharma GmbH (DE) 1988-06-01 EP claimed
US-4740306-A STRONG CATIIONIC EXCHANGE RESIN, TRIAZINE DYE AND WEAK ANIONIC EXCHANGE RESIN TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1988-04-26 US claimed
US-4721572-A CHROMATOGRAPHY MILES LABORATORIES, INC. (US) 1988-01-26 US claimed
EP-0208215-A2 Purification of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices MILES INC. (US) 1987-01-14 EP claimed
EP-0040124-B1 HYDROPHILIC COPOLYMERS BASED ON N-TRIS(HYDROXY-METHYL)METHYLACRYL AMIDE, PROCESS FOR THEIR PREPARATION, AQUEOUS GEL OF THESE COPOLYMERS AND THEIR USE AS ION EXCHANGERS PHARMUKA LABORATOIRES (FR) 1985-03-27 EP claimed
US-4452916-A Hydrophilic copolymers based on N-[tris(hydroxymethyl)methyl]-acrylamide, processes for their preparation, aqueous gels of said copolymers and their use as ion exchangers PHARMINDUSTRIE (FR) 1984-06-05 US claimed
EP-0040124-A1 Hydrophilic copolymers based on N-tris(hydroxy-methyl)methylacryl amide, process for their preparation, aqueous gel of these copolymers and their use as ion exchangers PHARMUKA LABORATOIRES (FR) 1981-11-18 EP claimed
US-4192784-A N-(TRIS(HYDROXYMETHYL)METHYL)ACRYLAMIDE OR THE METHACRYLAMIDE COPOLYMERS, BIOLOGICAL IMMOBILIZATION MAR-PHA SOCIETE D'ETUDES ET D'EXPLOITATION DE MARQUES (FR) 1980-03-11 US claimed