SCHEMBL8841271

SCHEMBL8841271

C=CC(=O)N=C=O.C=CC(=O)NC(CO)(CO)CO

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105869 0.82 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL29365042 0.78 ALDH1A1 (0.39) ALDH1A1MAPK1CYP3A4
SCHEMBL155360 0.75
Bromide SCHEMBL11652649 0.73
SCHEMBL7637582 0.73 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL17506759 0.72 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL7037814 0.71 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL16900645 0.71 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1TDP1CYP3A4
SCHEMBL275376 0.71 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TDP1CYP3A4
Acrylic Acid SCHEMBL21409768 0.69 LMNA (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0809103-A2 Stable denaturants for use in electrophoretic techniques and methods of using the same FMC CORPORATION (US) 1997-11-26 EP disclosed