Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11236238 | 0.99 | HRH2 (0.39) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL10439042 | 0.99 | HRH2 (0.39) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL9817424 | 0.89 | HRH2 (0.40) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL10586317 | 0.88 | HRH2 (0.37) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL8487525 | 0.87 | AOC3 (0.39) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL10539430 | 0.87 | HRH2 (0.37) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11249705 | 0.87 | HRH2 (0.44) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL8411573 | 0.86 | KMT2A (0.35) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL10934527 | 0.86 | AOC3 (0.38) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL8481908 | 0.86 | AOC3 (0.38) | HRH2SLC22A2CA12SLC22A3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322335-A1 | New-quanidino-thiazol compounds, their preparation, and use as intermediates of famotidine process | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1989-06-28 | — | — | EP | disclosed |
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |