Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8481908 | 0.99 | AOC3 (0.38) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| Hydrochloric Acid SCHEMBL10934527 | 0.99 | AOC3 (0.38) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| SCHEMBL11002732 | 0.92 | AOC3 (0.37) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| Hydrochloric Acid SCHEMBL11259470 | 0.91 | AOC3 (0.36) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| SCHEMBL10587291 | 0.87 | HRH2 (0.39) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| SCHEMBL8411573 | 0.87 | KMT2A (0.35) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| Hydrochloric Acid SCHEMBL10439042 | 0.86 | HRH2 (0.39) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| Hydrochloric Acid SCHEMBL11236238 | 0.86 | HRH2 (0.39) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| SCHEMBL8411615 | 0.85 | KMT2A (0.34) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 | |
| SCHEMBL9817424 | 0.85 | HRH2 (0.40) | AOC3KMT2ASMN1; SMN2HRH2SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094303-B1 | AMIDES, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI S.A. (FR) | 1985-11-06 | — | — | EP | claimed |
| EP-0094303-A1 | Amides, their salts, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1983-11-16 | — | — | EP | claimed |
| US-4262126-A | INHIBIT SECRETION OF GASTRIC JUICE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-14 | — | — | US | claimed |
| JP-62175474-A | — | — | None | — | — | JP | disclosed |
| US-6005115-A | HISTAMINE H.SUB.2-RECEPTOR ANTAGONIST, USEFUL IN THERAPY AS AN ACID SECRETION INHIBITOR | FERRER INTERNACIONAL, S.A. (ES) | 1999-12-21 | — | — | US | disclosed |
| EP-0738721-A1 | FORMS A AND B OF N-[[[2-[[[2-[(DIAMINOMETHYLEN)AMINO]-4-THIAZOLYL]METHYL]THIO]ETHYL]AMINO]METHYLEN]-4-BROMOBENZENOSULPHONAMIDE | FERRER INTERNACIONAL, S.A. (ES) | 1996-10-23 | — | — | EP | disclosed |
| US-5212187-A | Antihistamines | ZYMA SA (CH) | 1993-05-18 | — | — | US | disclosed |
| EP-0526395-A1 | Arylalkylamine derivatives, process for their preparation and pharmaceutical compositions containing them | Zyma SA (CH) | 1993-02-03 | — | — | EP | disclosed |
| US-5171860-A | Diamino isothiazole-1-oxides and 1,1 dioxides as gastric secretion inhibitors | MERCK & CO., INC. (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0159012-B1 | SULFONAMIDINES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-02-01 | — | — | EP | disclosed |
| US-4772704-A | ANTIULCER AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4307104-A | BLOCKING HISTAMINE H2 RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-22 | — | — | US | disclosed |
| EP-0040696-A2 | Aminothiadiazoles as gastric secretion inhibitors | MERCK & CO. INC. (US) | 1981-12-02 | — | — | EP | disclosed |
| EP-0028482-A1 | Guanidine compounds, process for preparing them and compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-05-13 | — | — | EP | disclosed |
| US-4262126-A | INHIBIT SECRETION OF GASTRIC JUICE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-14 | — | — | US | disclosed |
| EP-0015138-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-09-03 | — | — | EP | disclosed |
| EP-0010894-A1 | Antisecretory heterocyclic guanidine derivatives, process for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-05-14 | — | — | EP | disclosed |
| EP-0010418-A1 | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |
| US-4200578-A | ANTIULCER AGENTS, BLOCKING AGENTS, ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-4165378-A | ANTISECRETORY, ANTIHISTAMINE | ICI AMERICAS INC. (US) | 1979-08-21 | — | — | US | disclosed |