Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.42 |
| ▸ | F11 | P03951 | 4/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | F9 | P00740 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.42 |
| ▸ | PLAT | P00750 | 3/20 | 0.42 |
| ▸ | F7 | P08709 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594523 | 0.84 | AKR1B1 (0.37) | CFDF11KLKB1F2F9 | |
| SCHEMBL7972501 | 0.78 | PARP1 (0.41) | CYP2C9ACHE | |
| SCHEMBL19973594 | 0.78 | PARP1 (0.41) | CYP2C9ACHE | |
| SCHEMBL21456844 | 0.78 | ACHE (0.47) | CFDF11KLKB1AKR1B1TDP1 | |
| SCHEMBL10586303 | 0.77 | PTGDR2 (0.49) | CFDF11KLKB1F2F9 | |
| Hydrochloric Acid SCHEMBL19974004 | 0.77 | PARP1 (0.40) | CYP2C9ACHE | |
| Hydrochloric Acid SCHEMBL19974005 | 0.77 | PARP1 (0.40) | CYP2C9ACHE | |
| SCHEMBL10586188 | 0.75 | CFD (0.37) | CFDF11KLKB1F2F9 | |
| SCHEMBL10587133 | 0.74 | USP2 (0.44) | TDP1P2RX7 | |
| SCHEMBL10586351 | 0.73 | GBA1 (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882353-A | ANTICOAGULANTS, VASODILATION, AND BRONCHODILATOR AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0315009-A2 | Chroman derivatives, process for their preparation and their use in medicines | BAYER AG (DE) | 1989-05-10 | — | — | EP | disclosed |