Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297959 | 0.80 | HDAC3 (0.45) | TAAR1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL1697450 | 0.79 | CYP1A2 (0.48) | TAAR1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL7318322 | 0.79 | TAAR1 (0.44) | TAAR1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL7266826 | 0.78 | MME (0.45) | SLC6A2SLC6A4SLC6A3TSHRCYP1A2 | |
| SCHEMBL7300322 | 0.77 | CNR2 (0.44) | SIGMAR1 | |
| SCHEMBL27758693 | 0.77 | CYP1A2 (0.46) | TAAR1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19812641 | 0.77 | EPHX1 (0.43) | HTR2AHRH1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL6946871 | 0.77 | CYP1A2 (0.39) | TAAR1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL277772 | 0.76 | LAP3 (0.41) | TAAR1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL7294571 | 0.76 | CSNK1E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327877-A2 | Peptide-renininhibitors | MERCK PATENT GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |