Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587702 | 1.00 | AGTR1 (0.45) | AGTR1AGTR2FOLH1PPARG | |
| SCHEMBL136 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL138 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL10586965 | 0.88 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL10586958 | 0.88 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL417 | 0.82 | SLC6A4 (0.46) | AGTR1AGTR2 | |
| SCHEMBL419 | 0.82 | SLC6A4 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8735381 | 0.81 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL10587698 | 0.81 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL7327261 | 0.80 | AGTR1 (0.54) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | claimed |