Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.68 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.68 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792485 | 0.91 | AGTR1 (0.64) | AGTR1AGTR2GP6 | |
| SCHEMBL33 | 0.90 | AGTR1 (0.75) | AGTR1AGTR2GP6 | |
| SCHEMBL10589434 | 0.87 | AGTR1 (0.82) | AGTR1AGTR2 | |
| SCHEMBL9214999 | 0.87 | AGTR1 (0.65) | AGTR1AGTR2GP6 | |
| SCHEMBL10587698 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2GP6 | |
| SCHEMBL8916330 | 0.84 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9856412 | 0.83 | AGTR2 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8913829 | 0.83 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8076001 | 0.83 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL965839 | 0.82 | AGTR1 (0.67) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733366-B1 | Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics | DU PONT (US) | 1998-04-01 | — | — | EP | claimed |