Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602005 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAS1PR2NPSR1MAPK1 | |
| SCHEMBL8596001 | 0.99 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAS1PR2NPSR1MAPK1 | |
| SCHEMBL6718844 | 0.95 | MAPT (0.50) | SMN1; SMN2LMNAS1PR2NPSR1MAPK1 | |
| SCHEMBL6098673 | 0.94 | MAPT (0.52) | SMN1; SMN2LMNAMAPK1CHRM2CHRM1 | |
| SCHEMBL4314418 | 0.89 | ADRA1A (0.49) | SMN1; SMN2LMNAMAPK1CHRM2CHRM1 | |
| SCHEMBL5361174 | 0.89 | ADRA1A (0.49) | SMN1; SMN2LMNAMAPK1CHRM2CHRM1 | |
| SCHEMBL10735416 | 0.89 | PRKCQ (0.46) | SMN1; SMN2LMNAS1PR2NPSR1MAPK1 | |
| SCHEMBL4143499 | 0.88 | MAPT (0.50) | SMN1; SMN2LMNAMAPK1HTTCHRM2 | |
| SCHEMBL4316365 | 0.88 | MAPT (0.50) | SMN1; SMN2LMNAMAPK1HTTCHRM2 | |
| SCHEMBL4321129 | 0.88 | ADRA1A (0.50) | SMN1; SMN2LMNAMAPK1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-A1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1989-04-12 | — | — | EP | disclosed |