Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361174 | 0.95 | ADRA1A (0.49) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL4314418 | 0.95 | ADRA1A (0.49) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL10587724 | 0.94 | SMN1; SMN2 (0.51) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL4143499 | 0.94 | MAPT (0.50) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL4316365 | 0.94 | MAPT (0.50) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL9602005 | 0.94 | SMN1; SMN2 (0.51) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL4321129 | 0.93 | ADRA1A (0.50) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL8596001 | 0.92 | SMN1; SMN2 (0.49) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL1335235 | 0.92 | POLB (0.51) | MAPTMEN1KMT2ATDP1BCHE | |
| SCHEMBL5358407 | 0.92 | CHRM2 (0.48) | MAPTMEN1KMT2ATDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112677-B2 | 1H-imidazo dimers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-09-26 | — | — | US | disclosed |
| US-20050026947-A1 | 1H-imidazo dimers | 3M INNOVATIVE PROPERTIES COMPANY | 2005-02-03 | — | — | US | disclosed |
| US-6818650-B2 | 1H-IMIDAZO(4,5-C)- QUINOLINE OR -PYRIDINE DERIVATIVES; INDUCE BIOSYNTHESIS OF CYTOKINES; VIRAL DISEASES; ANTICARCINOGENIC AND ANTITUMOR AGENTS; IMMUNOMODULATORS | 3M INNOVATIVE PROPERTIES COMPANY | 2004-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026947-A1 | 1H-imidazo dimers | IL2, EIF2AK2, IRF3 | MAPT 3231/4885MEN1 2633/4885KMT2A 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.