Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587667 | 0.85 | ALDH1A1 (0.41) | PKMALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10587814 | 0.83 | PKM (0.36) | PKMALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL10389921 | 0.79 | ALDH1A1 (0.37) | PKMALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9586618 | 0.78 | ALDH1A1 (0.36) | PKMALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10590091 | 0.76 | PKM (0.42) | PKMALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL10609185 | 0.75 | PKM (0.47) | PKMALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10589301 | 0.74 | ALDH1A1 (0.33) | PKMALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL10589883 | 0.73 | PTPN1 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL39558 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL10496955 | 0.73 | PKM (0.38) | PKMALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335156-A1 | 5-Amino-1-phenylpyrazoles | BAYER AG (DE) | 1989-10-04 | — | — | EP | disclosed |