SCHEMBL10587774

SCHEMBL10587774

CC1CSC(=O)N1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.41
ALDH1A1 P00352 3/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.41
G6PD P11413 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 2/20 0.40
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
MAOA P21397 1/20 0.37
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31223207 0.84 ALDH1A1 (0.40) ALDH1A1MAPTHPGDSMN1; SMN2L3MBTL1
SCHEMBL10588437 0.79 GAA (0.35) KIF11ALDH1A1USP2POLBMAPT
SCHEMBL27686342 0.76 ALDH1A1 (0.40) ALDH1A1MAPTSMN1; SMN2GAANPSR1
SCHEMBL27279146 0.73 MAPT (0.51) ALDH1A1USP2POLBMAPTHPGD
SCHEMBL3920542 0.72 ALDH1A1 (0.43) ALDH1A1USP2POLBMAPTHPGD
SCHEMBL6713101 0.70 MAOA (0.48) ALDH1A1USP2POLBMAPTHPGD
SCHEMBL609915 0.69 NOTUM (0.42) ALDH1A1USP2POLBMAPTHPGD
SCHEMBL31663152 0.69 GAA (0.44) KIF11ALDH1A1USP2POLBMAPT
SCHEMBL27705351 0.69 ALDH1A1 (0.38) KIF11ALDH1A1USP2POLBMAPT
SCHEMBL2234874 0.69 GAA (0.44) KIF11ALDH1A1USP2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101132760-A Agent and method for colouring keratin fibres PROCTER & GAMBLE (US) 2008-02-27 CN claimed
CN-101132760-A Agent and method for colouring keratin fibres PROCTER & GAMBLE (US) 2008-02-27 CN disclosed
EP-0320910-A1 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1989-06-21 EP disclosed