SCHEMBL10587793

SCHEMBL10587793

C=CC(CC(N)=O)C(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
AKT1 P31749 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
MAPT P10636 3/20 0.41
CYP2C19 P33261 3/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 2/20 0.41
POLB P06746 1/20 0.41
PARP1 P09874 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MDM2 Q00987 1/20 0.41
HTT P42858 2/20 0.39
MAPK1 P28482 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11088938 0.77 MDM2 (0.59) LMNAAKT1L3MBTL1TDP1MAPT
SCHEMBL9796632 0.76 MEN1 (0.48) LMNAMAPTTSHRNPC1PGR
SCHEMBL14539497 0.76 KEAP1 (0.43) LMNATDP1MAPTMDM2HTT
SCHEMBL10587782 0.76 TSHR (0.50) LMNAAKT1L3MBTL1TDP1MAPT
SCHEMBL24095826 0.74 TDP1 (0.46) LMNAL3MBTL1TDP1MAPTCYP2C19
SCHEMBL7383020 0.74 TDP1 (0.46) LMNAL3MBTL1TDP1MAPTCYP2C19
SCHEMBL29750283 0.74 TDP1 (0.46) LMNAL3MBTL1TDP1MAPTCYP2C19
SCHEMBL7383022 0.74 CES1 (0.48) LMNAL3MBTL1TDP1MAPTCYP2C19
SCHEMBL1712976 0.73 BLM (0.35) CYP2C19TSHRBLMPMP22ALDH1A1
SCHEMBL24513224 0.73 BLM (0.35) CYP2C19TSHRBLMPMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300325-A2 Compositions for promoting growth of animals COMETEC S.r.l. (IT) 1989-01-25 EP disclosed