Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405059 | 0.79 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1414563 | 0.77 | TSHR (0.55) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10587793 | 0.76 | LMNA (0.42) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7882975 | 0.75 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19346894 | 0.75 | L3MBTL1 (0.56) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7203018 | 0.75 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11762210 | 0.75 | TSHR (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11088941 | 0.74 | ALDH1A1 (0.53) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2679188 | 0.73 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28049900 | 0.73 | L3MBTL1 (0.62) | TSHRL3MBTL1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300325-A2 | Compositions for promoting growth of animals | COMETEC S.r.l. (IT) | 1989-01-25 | — | — | EP | disclosed |