Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SHBG | P04278 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597989 | 0.84 | SERPINA6 (0.48) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL10587871 | 0.81 | SERPINA6 (0.38) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL8214356 | 0.71 | SERPINA6 (0.44) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL24476230 | 0.69 | ALDH1A1 (0.69) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL28411666 | 0.69 | ALDH1A1 (0.69) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL19219845 | 0.69 | ALDH1A1 (0.69) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL3719327 | 0.69 | ALDH1A1 (0.69) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL11517687 | 0.69 | MAPT (0.49) | SERPINA6ALDH1A1SHBGSLC22A1THRB | |
| SCHEMBL8507978 | 0.68 | CYP3A4 (0.70) | SERPINA6ALDH1A1SHBGMAPTABCB11 | |
| SCHEMBL6514713 | 0.68 | CYP3A4 (0.70) | SERPINA6ALDH1A1SHBGMAPTABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327766-A2 | Redox systems for brain-targeted drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-08-16 | — | — | EP | claimed |