Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 5/20 | 0.70 |
| ▸ | PGR | P06401 | 5/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.70 |
| ▸ | AR | P10275 | 4/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514713 | 1.00 | CYP3A4 (0.70) | CYP3A4ABCB11PGRCYP2C19AR | |
| SCHEMBL6513528 | 0.88 | PGR (0.58) | CYP3A4ABCB11PGRCYP2C19AR | |
| SCHEMBL8510434 | 0.83 | SHBG (0.55) | CYP3A4ABCB11PGRCYP2C19AR | |
| SCHEMBL8510437 | 0.83 | SHBG (0.55) | CYP3A4ABCB11PGRCYP2C19AR | |
| SCHEMBL9555269 | 0.83 | SHBG (0.55) | CYP3A4ABCB11PGRCYP2C19AR | |
| SCHEMBL11291553 | 0.83 | CYP3A4 (0.85) | CYP3A4ABCB11PGRCYP2C19AR | |
| Norethindrone Acetate SCHEMBL37530 | 0.83 | CYP3A4 (1.00) | CYP3A4ABCB11PGRCYP2C19AR | |
| Norethindrone Acetate SCHEMBL11321479 | 0.83 | CYP3A4 (1.00) | CYP3A4ABCB11PGRCYP2C19AR | |
| Norethindrone Acetate SCHEMBL14577826 | 0.83 | CYP3A4 (1.00) | CYP3A4ABCB11PGRCYP2C19AR | |
| Norethindrone Acetate SCHEMBL1232662 | 0.83 | CYP3A4 (1.00) | CYP3A4ABCB11PGRCYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335545-B2 | Pharmaceutical formulations for parenteral use | UNIV FLORIDA (US) | 1998-09-23 | — | — | EP | claimed |
| EP-0327766-B1 | Redox systems for brain-targeted drug delivery | UNIV FLORIDA (US) | 1998-04-08 | — | — | EP | claimed |
| US-5024998-A | Administering in aqueous solution with cyclodextrin derivative | UNIVERSITY OF FLORIDA (US) | 1991-06-18 | — | — | US | claimed |
| US-5017566-A | Redox systems for brain-targeted drug delivery | UNIVERSITY OF FLORIDA (US) | 1991-05-21 | — | — | US | claimed |
| US-5002935-A | Inclusion Complexing Hydroxypropylcyclodextrin with a Dihydropyridine-substituted Drug | UNIVERSITY OF FLORIDA (US) | 1991-03-26 | — | — | US | claimed |
| EP-0579435-B1 | Cyclodextrin complexation | CYCLOPS H F (IS) | 1999-03-17 | — | — | EP | disclosed |
| EP-0335545-B2 | Pharmaceutical formulations for parenteral use | UNIV FLORIDA (US) | 1998-09-23 | — | — | EP | disclosed |
| EP-0327766-B1 | Redox systems for brain-targeted drug delivery | UNIV FLORIDA (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5472954-A | Combining cyclodextrin with polymer before adding active material | CYCLOPS H.F. (IS) | 1995-12-05 | — | — | US | disclosed |
| US-5324718-A | Complexing with natural and synthetic polymers; high speed drug release | CYCLOPS H.F. (IS) | 1994-06-28 | — | — | US | disclosed |
| EP-0579435-A1 | Cyclodextrin complexation | CYCLOPS h.f. (IS) | 1994-01-19 | — | — | EP | disclosed |
| US-5024998-A | Administering in aqueous solution with cyclodextrin derivative | UNIVERSITY OF FLORIDA (US) | 1991-06-18 | — | — | US | disclosed |
| US-5017566-A | Redox systems for brain-targeted drug delivery | UNIVERSITY OF FLORIDA (US) | 1991-05-21 | — | — | US | disclosed |
| US-5002935-A | Inclusion Complexing Hydroxypropylcyclodextrin with a Dihydropyridine-substituted Drug | UNIVERSITY OF FLORIDA (US) | 1991-03-26 | — | — | US | disclosed |
| US-4983586-A | Decreasing precipitation at injection site or in lungs or other organs by combining with hydroxypropyl-beta-cyclodextrin | UNIVERSITY OF FLORIDA (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0335545-A2 | Pharmaceutical formulations for parenteral use | UNIVERSITY OF FLORIDA (US) | 1989-10-04 | — | — | EP | disclosed |
| EP-0327766-A2 | Redox systems for brain-targeted drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-08-16 | — | — | EP | disclosed |