SCHEMBL10588201

SCHEMBL10588201

O=Cc1ccc(-c2ccccc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
HPGD P15428 1/20 0.58
BCL2L1 Q07817 1/20 0.58
HSD17B10 Q99714 1/20 0.58
DRD1 P21728 3/20 0.51
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
DRD5 P21918 1/20 0.50
DRD3 P35462 1/20 0.50
ALDH5A1 P51649 1/20 0.48
ABAT P80404 1/20 0.48
CYP2A6 P11509 1/20 0.46
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
KDM1A O60341 3/20 0.44
ESR2 Q92731 1/20 0.44
KDM4E B2RXH2 2/20 0.43
PTGS2 P35354 1/20 0.43
RAB9A P51151 1/20 0.43
HTR2B P41595 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylphenol SCHEMBL28116733 0.90 ALDH1A1 (0.68) ALDH1A1HPGDBCL2L1HSD17B10DRD1
SCHEMBL1666926 0.84 DRD1 (0.60) ALDH1A1HSD17B10DRD1DRD2DRD4
SCHEMBL29733609 0.82 DRD1 (0.58) ALDH1A1HSD17B10DRD1DRD2DRD4
SCHEMBL29733602 0.82 DRD1 (0.58) ALDH1A1HSD17B10DRD1DRD2DRD4
SCHEMBL714236 0.82 ALDH1A1 (0.83) ALDH1A1HPGDBCL2L1HSD17B10KDM1A
SCHEMBL29443997 0.82 ALDH1A1 (0.83) ALDH1A1HPGDBCL2L1HSD17B10KDM1A
SCHEMBL29575050 0.81 ALDH1A1 (0.55) ALDH1A1HPGDBCL2L1HSD17B10KDM1A
SCHEMBL35966 0.80 ALDH1A1 (0.59) ALDH1A1HPGDBCL2L1HSD17B10DRD1
SCHEMBL12005282 0.80 PELI1 (0.53) ALDH1A1HPGDBCL2L1HSD17B10DRD1
SCHEMBL18189724 0.79 ALDH1A1 (0.79) ALDH1A1HPGDBCL2L1HSD17B10KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320346-A2 Process for preparing hydroxylated aromatic derivatives by way of the Bayer-Villiger reaction RHONE-POULENC CHIMIE (FR) 1989-06-14 EP disclosed