2-Phenylphenol

2-Phenylphenol

SCHEMBL28116733

O=Cc1ccccc1.Oc1ccccc1-c1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
HPGD P15428 1/20 0.68
BCL2L1 Q07817 1/20 0.68
HSD17B10 Q99714 1/20 0.68
CYP2A6 P11509 1/20 0.56
BACE1 P56817 1/20 0.46
ALOX5 P09917 1/20 0.45
HDAC6 Q9UBN7 2/20 0.44
KDM1A O60341 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
DRD1 P21728 3/20 0.42
PELI1 Q96FA3 1/20 0.42
BRD4 O60885 1/20 0.42
NR1I2 O75469 1/20 0.42
SMARCA2 P51531 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10588201 0.90 ALDH1A1 (0.58) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
SCHEMBL13762175 0.85 KDM1A (0.56) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
Benzaldehyde SCHEMBL29224678 0.83 ALDH1A1 (0.74) ALDH1A1HPGDHSD17B10CYP2A6ALOX5
2-Phenylphenol SCHEMBL29811 0.82 ALDH1A1 (1.00) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
2-Phenylphenol SCHEMBL14249267 0.82 ALDH1A1 (1.00) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
SCHEMBL28366972 0.82 ALDH1A1 (1.00) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
2-Phenylphenol SCHEMBL29360750 0.82 ALDH1A1 (1.00) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
2-Phenylphenol SCHEMBL27831345 0.82 ALDH1A1 (1.00) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
2-Phenylphenol SCHEMBL2415939 0.81 ALDH1A1 (0.85) ALDH1A1HPGDBCL2L1HSD17B10BACE1
2-Phenylphenol SCHEMBL8617992 0.81 HPGD (0.85) ALDH1A1HPGDBCL2L1HSD17B10BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279704-A Polyphenyl ether modified phenol-benzaldehyde polyfunctional epoxy resin and purposes 南亚塑胶工业股份有限公司 2017-01-04 CN disclosed