Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822346 | 0.77 | POLB (0.48) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL8961272 | 0.74 | POLB (0.43) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL5596192 | 0.74 | CYP3A4 (0.43) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL1527604 | 0.74 | TSHR (0.48) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL4462235 | 0.74 | POLB (0.50) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL3904945 | 0.74 | POLB (0.50) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL193239 | 0.74 | TSHR (0.48) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL9050380 | 0.73 | POLB (0.46) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL28625168 | 0.72 | POLB (0.42) | POLBTSHRGAAL3MBTL1CYP3A4 | |
| Bromide SCHEMBL31119163 | 0.72 | TSHR (0.46) | POLBTSHRGAAL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331550-A1 | Novel aspartate transcarbamylase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-06 | — | — | EP | disclosed |