Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961431 | 0.83 | HMGCR (0.36) | POLBGAACYP3A4HMGCR | |
| SCHEMBL8961388 | 0.80 | CYP3A4 (0.47) | GAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL3822346 | 0.77 | POLB (0.48) | POLBGAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL8961321 | 0.77 | CYP2C19 (0.44) | CYP2C19 | |
| SCHEMBL22034596 | 0.77 | TSHR (0.46) | POLBGAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL1585013 | 0.77 | TSHR (0.46) | POLBGAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL9614470 | 0.76 | TSHR (0.50) | POLBGAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL20558035 | 0.75 | POLB (0.47) | POLBGAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL5596192 | 0.74 | CYP3A4 (0.43) | POLBGAATSHRL3MBTL1CYP3A4 | |
| SCHEMBL10588317 | 0.74 | POLB (0.43) | POLBGAATSHRL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532402-A | Process for producing optically active hydroxyalkylphosphonates | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-07-02 | — | — | US | disclosed |