Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588330 | 1.00 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL14191673 | 0.91 | NR1I2 (0.48) | LMNAHTTKDM4EMAPTNPSR1 | |
| SCHEMBL9220790 | 0.89 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL9214819 | 0.88 | MAPT (0.43) | KMT2ALMNAKDM4EMAPTNPSR1 | |
| SCHEMBL9220052 | 0.85 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL9214586 | 0.84 | LMNA (0.46) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL9197768 | 0.82 | HRH3 (0.53) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL9219673 | 0.81 | NPC1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL15004872 | 0.81 | HRH3 (0.60) | HRH3KCNH2 | |
| SCHEMBL9218533 | 0.81 | KDM4E (0.43) | MEN1KMT2ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320032-A1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-14 | — | — | EP | disclosed |