SCHEMBL1058836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27289016	0.87	SMN1; SMN2 (0.46)	KDM4ESMN1; SMN2MAPK1HPGDCYP1A2
	SCHEMBL1059979	0.86	KDM4E (0.48)	KDM4ESMN1; SMN2MAPK1HPGDHSD17B10
	SCHEMBL1055154	0.85	MAPK1 (0.53)	KDM4ESMN1; SMN2MAPK1HPGDHSD17B10
	SCHEMBL12651960	0.82	MAPK1 (0.57)	KDM4ESMN1; SMN2MAPK1HPGDCYP2C9
	SCHEMBL8804535	0.74	HSD17B10 (0.43)	KDM4ESMN1; SMN2MAPK1HPGDCYP1A2
	SCHEMBL1748473	0.74	MAPK1 (0.46)	KDM4EMAPK1HPGDHSD17B10ALDH1A1
	SCHEMBL5844147	0.74	MAPK1 (0.46)	KDM4EMAPK1HPGDCYP1A2CYP2C9
	SCHEMBL17926536	0.74	MAPK1 (0.48)	KDM4ESMN1; SMN2MAPK1HPGDHSD17B10
	SCHEMBL1060382	0.72	MAPK1 (0.56)	KDM4ESMN1; SMN2MAPK1HPGDHSD17B10
	SCHEMBL1059503	0.72	KDM4E (0.57)	KDM4ESMN1; SMN2HPGDCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.