SCHEMBL1058902

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5605835	0.86	CYP3A4 (0.48)	ALDH1A1HSD17B10TDP1CYP3A4TSHR
	SCHEMBL19494021	0.80	TDP1 (0.61)	ALDH1A1HSD17B10TDP1CYP3A4TSHR
	SCHEMBL3783607	0.79	HDAC2 (0.46)	ALDH1A1HSD17B10TDP1CYP3A4TSHR
	SCHEMBL5604523	0.79	PRKCI (0.47)	ALDH1A1HSD17B10TDP1CYP3A4TSHR
	SCHEMBL3785608	0.77	HDAC2 (0.62)	ALDH1A1HSD17B10MEN1KMT2AKDM4E
	Water SCHEMBL28643226	0.77	HDAC2 (0.45)	ALDH1A1HSD17B10TDP1CYP3A4TSHR
	SCHEMBL3784612	0.74	MAP4K4 (0.53)	CYP3A4MEN1HDAC2HDAC3HDAC1
	SCHEMBL27403385	0.74	CYP3A4 (0.56)	ALDH1A1HSD17B10TDP1CYP3A4TSHR
	SCHEMBL13211386	0.72	NR4A1 (0.54)	ALDH1A1TDP1CYP3A4TSHRMEN1
	SCHEMBL3321703	0.71	HSD17B10 (0.71)	ALDH1A1HSD17B10TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.