Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068254 | 0.81 | NUDT1 (0.57) | HDAC2NUDT1BACE1HSP90AA1 | |
| SCHEMBL16581487 | 0.78 | NUDT1 (0.51) | ERN1HDAC2NUDT1BACE1HSP90AA1 | |
| SCHEMBL9644050 | 0.74 | NUDT1 (0.51) | NUDT1BACE1HSP90AA1 | |
| SCHEMBL2718435 | 0.74 | NUDT1 (0.51) | NUDT1BACE1HSP90AA1 | |
| SCHEMBL2718548 | 0.74 | NUDT1 (0.51) | NUDT1BACE1HSP90AA1 | |
| SCHEMBL6068103 | 0.73 | ERN1 (0.64) | ERN1HDAC2HDAC1HDAC3KCNH2 | |
| SCHEMBL29744559 | 0.73 | ERN1 (0.64) | ERN1HDAC2HDAC1HDAC3KCNH2 | |
| SCHEMBL7081630 | 0.73 | NUDT1 (0.50) | HDAC2NUDT1BACE1HSP90AA1 | |
| SCHEMBL10589672 | 0.72 | NUDT1 (0.43) | NUDT1BACE1HSP90AA1 | |
| SCHEMBL10428357 | 0.72 | HPGD (0.49) | NUDT1BACE1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331195-A2 | Acylphenol derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |