Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428351 | 0.79 | HSP90AA1 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| Dimethylamine SCHEMBL10428304 | 0.78 | ALOX5 (0.48) | HPGDRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL28509539 | 0.77 | HSP90AA1 (0.50) | HPGDRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL6931826 | 0.77 | HPGDS (0.59) | HPGDRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL10428302 | 0.76 | ALOX5 (0.45) | HPGDRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL313355 | 0.75 | KMO (0.54) | HTTALDH1A1MEN1KMT2APTGS2 | |
| Diethylamine SCHEMBL10428382 | 0.74 | ALOX5 (0.44) | HPGDRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL11054583 | 0.74 | HSP90AA1 (0.53) | RAB9ANPC1HTTALDH1A1MEN1 | |
| SCHEMBL14273035 | 0.74 | GAA (0.52) | HTTALDH1A1PTGS2HSP90AA1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10428381 | 0.73 | ALOX5 (0.43) | HPGDRAB9ANPC1HPGDSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927835-A | ANTIPYRETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |