Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL10589724

N.O=S(=O)(O)c1ccc(-c2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
TSHR P16473 2/20 0.59
ALDH1A1 P00352 2/20 0.59
NT5E P21589 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.57
TDP1 Q9NUW8 1/20 0.52
CA12 O43570 7/20 0.50
CA2 P00918 7/20 0.50
CA9 Q16790 7/20 0.50
POLB P06746 1/20 0.48
CYP2D6 P10635 1/20 0.48
ENPP2 Q13822 1/20 0.44
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CA1 P00915 4/20 0.42
CA14 Q9ULX7 3/20 0.42
MMP2 P08253 1/20 0.40
MMP7 P09237 1/20 0.40
MMP14 P50281 1/20 0.40
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3171676 0.97 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL447639 0.97 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL525918 0.97 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL29990536 0.97 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL9493276 0.94 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
Hydrochloric Acid SCHEMBL27965440 0.94 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL9302694 0.94 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
Potassium SCHEMBL30064005 0.94 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL9302668 0.94 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
Hydrochloric Acid SCHEMBL11161795 0.94 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325975-A1 Process for the production of alkali salts of biphenyl-4,4'-disulphonic acid BASF Aktiengesellschaft (DE) 1989-08-02 EP disclosed