SCHEMBL525918

SCHEMBL525918

O=S(=O)(O)c1ccc(-c2ccc(-c3ccc(-c4ccc(S(=O)(=O)O)cc4)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.65
TSHR P16473 3/20 0.62
ALDH1A1 P00352 3/20 0.62
NT5E P21589 1/20 0.62
SMN1; SMN2 Q16637 2/20 0.60
TDP1 Q9NUW8 2/20 0.54
CA12 O43570 7/20 0.52
CA2 P00918 7/20 0.52
CA9 Q16790 7/20 0.52
POLB P06746 1/20 0.50
CYP2D6 P10635 1/20 0.50
ENPP2 Q13822 1/20 0.46
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CA1 P00915 4/20 0.44
CA14 Q9ULX7 3/20 0.44
MMP2 P08253 1/20 0.41
MMP7 P09237 1/20 0.41
MMP14 P50281 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3171676 1.00 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL29990536 1.00 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL447639 1.00 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
Hydrochloric Acid SCHEMBL27965440 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL9493276 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
Potassium SCHEMBL30064005 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL9302668 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL9302694 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
Ammonia Solution, Strong SCHEMBL10589724 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2
Hydrochloric Acid SCHEMBL11161795 0.97 LMNA (0.62) LMNATSHRALDH1A1NT5ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010045529-A1 Double-resonance-absorption microscope OLYMPUS CORPORATION (JP) 2001-11-29 US claimed
EP-2675524-B1 DEVICE AND METHOD FOR TREATMENT OF CELLS AND CELL TISSUE MERCK PATENT GMBH (DE) 2017-05-10 EP disclosed
EP-2510072-B1 THERAPEUTIC AND COSMETIC ELECTROLUMINESCENT COMPOSITIONS MERCK PATENT GMBH (DE) 2016-12-21 EP disclosed
US-9492681-B2 Device and method for treatment of cells and cell tissue MERCK PATENT GMBH (DE) 2016-11-15 US disclosed
US-20160256053-A1 RADIATIVE FIBERS MERCK PATENT GMBH (DE) 2016-09-08 US disclosed
US-9373807-B2 Radiative fibers MERCK PATENT GMBH (DE) 2016-06-21 US disclosed
US-20140148877-A1 THERAPEUTIC AND COSMETIC ELECTROLUMINESCENT COMPOSITIONS MERCK PATENT GMBH (DE) 2014-05-29 US disclosed
EP-2675524-A1 DEVICE AND METHOD FOR TREATMENT OF CELLS AND CELL TISSUE Merck Patent GmbH (DE) 2013-12-25 EP disclosed
US-20130324909-A1 DEVICE AND METHOD FOR TREATMENT OF CELLS AND CELL TISSUE MERCK PATENT GMBH (DE) 2013-12-05 US disclosed
US-20130226268-A1 NANOCRYSTALS IN DEVICES MERCK PATENT GMBH (DE) 2013-08-29 US disclosed
WO-2012013270-A1 NANOCRYSTALS IN DEVICES MERCK PATENT GMBH (DE) 2012-02-02 WO disclosed
WO-2011110275-A2 RADIATIVE FIBERS MERCK PATENT GMBH (DE) 2011-09-15 WO disclosed
WO-2011069590-A1 THERAPEUTIC AND COSMETIC ELECTROLUMINESCENT COMPOSITIONS MERCK PATENT GMBH (DE) 2011-06-16 WO disclosed
EP-1182183-B1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO (JP) 2009-12-09 EP disclosed
US-20080241591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND PHENYLENEDIAMINE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-10-02 US disclosed
US-7399537-B2 Organic electroluminescence device and phenylenediamine derivative IDEMITSU KOSAN CO., LTD. (JP) 2008-07-15 US disclosed
US-20080091025-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-04-17 US disclosed
US-20070287029-A1 Aromatic Amine Compound and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-12-13 US disclosed
EP-1806334-A1 AROMATIC AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Idemitsu Kosan Co., Ltd. (JP) 2007-07-11 EP disclosed
EP-1395985-B1 HOLOGRAPHIC DATA-STORAGE MEDIUM TESA SCRIBOS GMBH (DE) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091025-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, SLC18A2, SLC43A1 LMNA 1999/4885TSHR 3746/4885ALDH1A1 1483/4885
US-20080241591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND PHENYLENEDIAMINE DERIVATIVE MAL2, L1CAM, EPCAM LMNA 927/4885TSHR 4652/4885ALDH1A1 734/4885
US-20070287029-A1 Aromatic Amine Compound and Organic Electroluminescent Device Using Same TYR, TRPA1, MAOA LMNA 2185/4885TSHR 2835/4885ALDH1A1 164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.