Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RABGGTB | P53611 | 2/20 | 0.32 |
| ▸ | RABGGTA | Q92696 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591992 | 1.00 | RABGGTB (0.32) | RABGGTBRABGGTABACE1CTSDSMN1; SMN2 | |
| SCHEMBL10591987 | 1.00 | RABGGTB (0.32) | RABGGTBRABGGTABACE1CTSDSMN1; SMN2 | |
| SCHEMBL9841957 | 0.83 | SMN1; SMN2 (0.35) | RABGGTBRABGGTABACE1CTSDSMN1; SMN2 | |
| SCHEMBL7286513 | 0.83 | SMN1; SMN2 (0.35) | RABGGTBRABGGTABACE1CTSDSMN1; SMN2 | |
| SCHEMBL7364784 | 0.83 | IL6ST (0.31) | — | |
| SCHEMBL9556791 | 0.82 | SPHK1 (0.34) | — | |
| SCHEMBL7365732 | 0.81 | RABGGTB (0.33) | RABGGTBRABGGTASMN1; SMN2 | |
| SCHEMBL7365730 | 0.81 | RABGGTB (0.33) | RABGGTBRABGGTASMN1; SMN2 | |
| SCHEMBL10593017 | 0.80 | KLK7 (0.38) | BACE1 | |
| SCHEMBL10593022 | 0.80 | KLK7 (0.38) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |