Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RABGGTB | P53611 | 2/20 | 0.33 |
| ▸ | RABGGTA | Q92696 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365732 | 1.00 | RABGGTB (0.33) | RABGGTBRABGGTASMN1; SMN2HCRTR2SPHK1 | |
| SCHEMBL7363618 | 0.85 | HCRTR2 (0.32) | HCRTR2EPHX1 | |
| SCHEMBL7363622 | 0.85 | HCRTR2 (0.32) | HCRTR2EPHX1 | |
| SCHEMBL7363627 | 0.85 | HCRTR2 (0.32) | HCRTR2EPHX1 | |
| SCHEMBL7361264 | 0.85 | RABGGTB (0.32) | RABGGTBRABGGTASMN1; SMN2 | |
| SCHEMBL9556791 | 0.84 | SPHK1 (0.34) | HCRTR2SPHK1EPHX1 | |
| SCHEMBL10528950 | 0.84 | SPHK1 (0.35) | RABGGTBRABGGTASMN1; SMN2HCRTR2SPHK1 | |
| SCHEMBL9556455 | 0.82 | SPHK1 (0.34) | HCRTR2SPHK1EPHX1 | |
| SCHEMBL9841957 | 0.82 | SMN1; SMN2 (0.35) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS | |
| SCHEMBL7286513 | 0.82 | SMN1; SMN2 (0.35) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |