Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592244 | 1.00 | PPARA (0.45) | PPARAPPARGMAPTNPSR1HPGD | |
| SCHEMBL9785787 | 0.91 | PPARA (0.46) | PPARAPPARGMAPTNPSR1HPGD | |
| SCHEMBL9785789 | 0.91 | PPARA (0.46) | PPARAPPARGMAPTNPSR1HPGD | |
| SCHEMBL28691194 | 0.89 | MAPT (0.47) | MAPTNPSR1SMN1; SMN2MEN1POLB | |
| SCHEMBL29358900 | 0.89 | MAPT (0.47) | MAPTNPSR1SMN1; SMN2MEN1POLB | |
| SCHEMBL203536 | 0.89 | MAPT (0.47) | MAPTNPSR1SMN1; SMN2MEN1POLB | |
| SCHEMBL29359005 | 0.86 | LMNA (0.44) | MAPTSMN1; SMN2POLBKMT2AMTNR1B | |
| SCHEMBL204215 | 0.86 | LMNA (0.44) | MAPTSMN1; SMN2POLBKMT2AMTNR1B | |
| SCHEMBL9150478 | 0.82 | RAB9A (0.46) | NPSR1HPGDMEN1POLBKMT2A | |
| SCHEMBL9150477 | 0.82 | RAB9A (0.46) | NPSR1HPGDMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341845-A2 | Fungicides | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |