Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | PYGB | P11216 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592883 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL2047734 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL8078537 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL23857823 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL3867600 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL23754212 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL874627 | 1.00 | SLC5A1 (0.39) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL4257861 | 0.87 | STAT3 (0.42) | GAALGALS8STAT3SLC28A3 | |
| SCHEMBL23350541 | 0.84 | LGALS8 (0.35) | SLC5A1PYGBALDH1A1THRBCD69 | |
| SCHEMBL4257855 | 0.81 | STAT3 (0.46) | ALDH1A1THRBMAPK1GAALGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710586-A1 | NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL | Silence Therapeutics GmbH (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-0340780-A2 | Azidochlorination and diazidization of glycals | BIOMIRA, INC. (CA) | 1989-11-08 | — | — | EP | disclosed |