SCHEMBL4257855

SCHEMBL4257855

CC(=O)NOC1O[C@H](CO[C@H]2C[C@@H](O)[C@@H](O)[C@@H](CO)O2)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 7/20 0.46
▸ LGALS8 O00214 2/20 0.42
▸ LGALS3 P17931 2/20 0.42
▸ LGALS4 P56470 2/20 0.42
▸ MAPK1 P28482 1/20 0.38
▸ MAPT P10636 1/20 0.37
▸ ACHE P22303 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ HDAC3 O15379 1/20 0.36
▸ HDAC4 P56524 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC7 Q8WUI4 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36
▸ HDAC10 Q969S8 1/20 0.36
▸ HDAC11 Q96DB2 1/20 0.36
▸ HDAC8 Q9BY41 1/20 0.36
▸ HDAC6 Q9UBN7 1/20 0.36
▸ HDAC9 Q9UKV0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4257861 0.91 STAT3 (0.42) STAT3LGALS8LGALS3LGALS4ACHE
SCHEMBL570049 0.83 ALDH1A1 (0.48) LGALS8LGALS3LGALS4MAPK1MAPT
SCHEMBL9943619 0.83 ALDH1A1 (0.48) LGALS8LGALS3LGALS4MAPK1MAPT
SCHEMBL570059 0.83 ALDH1A1 (0.48) LGALS8LGALS3LGALS4MAPK1MAPT
SCHEMBL9943621 0.83 ALDH1A1 (0.48) LGALS8LGALS3LGALS4MAPK1MAPT
SCHEMBL23754212 0.81 SLC5A1 (0.39) STAT3LGALS8MAPK1MAPTALDH1A1
SCHEMBL8078537 0.81 SLC5A1 (0.39) STAT3LGALS8MAPK1MAPTALDH1A1
SCHEMBL2047734 0.81 SLC5A1 (0.39) STAT3LGALS8MAPK1MAPTALDH1A1
SCHEMBL10592885 0.81 SLC5A1 (0.39) STAT3LGALS8MAPK1MAPTALDH1A1
SCHEMBL3867600 0.81 SLC5A1 (0.39) STAT3LGALS8MAPK1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10231907-B2 Compositions for improving the health and appearance of skin ALGENIST HOLDINGS, INC. (US) 2019-03-19 — — US disclosed
US-20150366791-A1 Compositions for Improving the Health and Appearance of Skin ALGENIST BRANDS LLC 2015-12-24 — — US disclosed
US-9095733-B2 Compositions for improving the health and appearance of skin SOLAZYME, INC. (US) 2015-08-04 — — US disclosed
US-8298548-B2 Compositions for improving the health and appearance of skin SOLAZYME, INC. (US) 2012-10-30 — — US disclosed
US-20120264177-A1 Compositions for Improving the Health and Appearance of Skin SOLAZYME, INC. (US) 2012-10-18 — — US disclosed
US-20090069213-A1 Compositions for Improving the Health and Appearance of Skin SOLAZYME, INC. (US) 2009-03-12 — — US disclosed
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