Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734210 | 0.84 | MAPT (0.69) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL6540877 | 0.83 | CA1 (0.50) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL30791016 | 0.83 | MAPT (0.67) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL1872295 | 0.83 | MAPT (0.67) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL7339301 | 0.82 | ALDH1A1 (0.46) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL6433557 | 0.81 | KDM4E (0.61) | MAPTKDM4EALDH1A1CYP1A2MEN1 | |
| SCHEMBL2746004 | 0.81 | MAPT (0.65) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL109163 | 0.81 | MAPT (0.74) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL7105545 | 0.81 | MAPT (0.74) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL26491275 | 0.80 | MAPT (0.63) | MAPTHSD17B10HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020032080-A1 | COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND | 学校法人慶應義塾 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020032080-A1 | COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND | 学校法人慶應義塾 | 2020-02-13 | — | — | WO | disclosed |
| WO-2019178547-A1 | BENZOXAZINE POLYMERS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |
| US-20130030192-A1 | Method of Synthesizing Acetonide-Protected Catechol-Containing Compounds and Intermediates Produced Therein | NORTHWESTERN UNIVERSITY | 2013-01-31 | — | — | US | disclosed |
| US-8227628-B2 | Method of synthesizing acetonide-protected catechol-containing compounds and intermediates produced therein | NORTHWESTERN UNIVERSITY (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100087622-A1 | Method of Synthesizing Acetonide-Protected Catechol-Containing Compounds and Intermediates Produced Therein | NORTHWESTERN UNIVERSITY (US) | 2010-04-08 | — | — | US | disclosed |
| EP-0347256-A2 | Method for detecting a substance in a sample | TOSOH CORPORATION (JP) | 1989-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087622-A1 | Method of Synthesizing Acetonide-Protected Catechol-Containing Compounds and Intermediates Produced Therein | DBH, COMT, PAH | MAPT 3973/4885HSD17B10 96/4885HIF1A 1487/4885 |
| US-20130030192-A1 | Method of Synthesizing Acetonide-Protected Catechol-Containing Compounds and Intermediates Produced Therein | DBH, COMT, PAH | MAPT 3973/4885HSD17B10 96/4885HIF1A 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.