Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138689 | 0.93 | MAPT (0.66) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL1709974 | 0.90 | MAPT (0.71) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL30252290 | 0.90 | MAPT (0.66) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL109163 | 0.89 | MAPT (0.74) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL6420228 | 0.87 | MAPT (0.72) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL107176 | 0.87 | MAPT (0.62) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL7108607 | 0.86 | MAPT (0.73) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL1278764 | 0.86 | MAPT (0.73) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL25380895 | 0.85 | MAPT (0.70) | MAPTHSD17B10HIF1AKDM4EALDH1A1 | |
| SCHEMBL109158 | 0.85 | MAPT (0.73) | MAPTHSD17B10HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | HAARMANN & REIMER GMBH (DE) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069307-A1 | 2-(3,4-Dihydroxyphenyl)ethyl-substituted carbonic acid derivatives and their use | NFE2L2, AGER, ME2 | MAPT 2276/4885HSD17B10 1254/4885HIF1A 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.