Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448182 | 0.97 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL10448020 | 0.87 | SPHK1 (0.38) | SPHK1 | |
| SCHEMBL9013476 | 0.84 | DRD2 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL10902210 | 0.82 | SPHK1 (0.60) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL9352982 | 0.80 | SPHK1 (0.59) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL10997251 | 0.80 | SPHK1 (0.68) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL7913866 | 0.80 | SPHK1 (0.59) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL10570956 | 0.80 | SPHK1 (0.68) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL9191131 | 0.80 | SPHK1 (0.68) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL10998246 | 0.80 | SPHK1 (0.63) | SPHK1SPHK2CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331933-A2 | Liquid crystal mixture with a low optical anisotropy | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |