SCHEMBL9013476

SCHEMBL9013476

CCCCCC1(CCCCC2CCC(c3ccccc3)CC2)CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.40
NPSR1 Q6W5P4 1/20 0.39
DRD1 P21728 1/20 0.38
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38
DRD3 P35462 1/20 0.38
ATM Q13315 1/20 0.37
CYP2C9 P11712 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
GRM2 Q14416 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
KDM1A O60341 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348118 0.95 DRD2 (0.40) DRD2DRD1DRD4DRD5DRD3
SCHEMBL9013468 0.86 OPRL1 (0.39) DRD2DRD1DRD4DRD5DRD3
SCHEMBL548269 0.85 DRD2 (0.49) DRD2DRD1DRD4DRD5DRD3
SCHEMBL548268 0.85 DRD2 (0.49) DRD2DRD1DRD4DRD5DRD3
SCHEMBL10593452 0.84 SPHK1 (0.46) CYP2C9MEN1KMT2AALDH1A1LMNA
SCHEMBL28160606 0.83 DRD2 (0.47) DRD2DRD1DRD4DRD5DRD3
SCHEMBL9751722 0.83 DRD2 (0.47) DRD2CYP2C9MEN1KMT2ACYP1A2
SCHEMBL10348257 0.83 DRD2 (0.47) DRD2CYP2C9MEN1KMT2ACYP1A2
SCHEMBL9013520 0.83 CYP2C9 (0.62) CYP2C9MEN1KMT2AALDH1A1LMNA
SCHEMBL9013292 0.83 CYP2C9 (0.47) CYP2C9MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed